The dominance and global influence of the United State of America put the 46th President of the United State, Joe Biden on a pedestal of influence on the world as it has been with his predecessors. The world is expected to experience a different turn, contrary to the Trump’s administration as President Biden assumes office. His administration is expected to have a profound impact on US foreign policy in Africa. This is obvious from his first action in office, reversing the Trump travel ban on some African countries, including Nigeria. It is also expected that Biden administration will encourage US – China trade, which will increase the growth of African countries in economic relationship with China.